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Structural Analysis of Dopamine- and Amphetamine-induced Depolarization Currents in the Human Dopamine Transporter

Amphetamine (AMPH) induces depolarizing currents through the human dopamine transporter (hDAT). Recently we discovered that the S(+) enantiomer of AMPH induces a current through hDAT that persists long after its removal from the external milieu. The persistent current is less prominent for R(−)AMPH...

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Detalhes bibliográficos
Publicado no:ACS Chem Neurosci
Main Authors: Tang, Qiong-Yao, Kolanos, Renata, De Felice, Louis J, Glennon, Richard A
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875417/
https://ncbi.nlm.nih.gov/pubmed/25594379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn500282f
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