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Process Analytical Technology for Advanced Process Control in Biologics Manufacturing with the Aid of Macroscopic Kinetic Modeling

Productivity improvements of mammalian cell culture in the production of recombinant proteins have been made by optimizing cell lines, media, and process operation. This led to enhanced titers and process robustness without increasing the cost of the upstream processing (USP); however, a downstream...

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Vydáno v:Bioengineering (Basel)
Hlavní autoři: Kornecki, Martin, Strube, Jochen
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874891/
https://ncbi.nlm.nih.gov/pubmed/29547557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering5010025
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