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Process Analytical Technology for Advanced Process Control in Biologics Manufacturing with the Aid of Macroscopic Kinetic Modeling

Productivity improvements of mammalian cell culture in the production of recombinant proteins have been made by optimizing cell lines, media, and process operation. This led to enhanced titers and process robustness without increasing the cost of the upstream processing (USP); however, a downstream...

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Detalhes bibliográficos
Publicado no:Bioengineering (Basel)
Main Authors: Kornecki, Martin, Strube, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874891/
https://ncbi.nlm.nih.gov/pubmed/29547557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering5010025
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