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Regulation of Hepatic UGT2B15 by Methylation in Adults of Asian Descent

The hepatic uridine 5′-diphosphate-glucuronosyl transferases (UGTs) are critical for detoxifying endo- and xenobiotics. Since UGTs are also dynamically responsive to endogenous and exogenous stimuli, we examined whether epigenetic DNA methylation can regulate hepatic UGT expression and differential...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Oeser, Steffen G., Bingham, Jon-Paul, Collier, Abby C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874819/
https://ncbi.nlm.nih.gov/pubmed/29316660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10010006
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