Pilocarpine-Induced Status Epilepticus Is Associated with P-Glycoprotein Induction in Cardiomyocytes, Electrocardiographic Changes, and Sudden Death

Sudden unexpected death in epilepsy (SUDEP) is the major cause of death in those patients suffering from refractory epilepsy (RE), with a 24-fold higher risk relative to the normal population. SUDEP risk increases with seizure frequency and/or seizure-duration as in RE and Status Epilepticus (SE). P...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Auzmendi, Jerónimo, Buchholz, Bruno, Salguero, Jimena, Cañellas, Carlos, Kelly, Jazmín, Men, Paula, Zubillaga, Marcela, Rossi, Alicia, Merelli, Amalia, Gelpi, Ricardo J., Ramos, Alberto J., Lazarowski, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874717/
https://ncbi.nlm.nih.gov/pubmed/29462915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph11010021
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