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Immunogenicity in African Green Monkeys of M Protein Mutant Vesicular Stomatitis Virus Vectors and Contribution of Vector-Encoded Flagellin

Recombinant vesicular stomatitis virus (VSV) is a promising platform for vaccine development. M51R VSV, an attenuated, M protein mutant strain, is an effective inducer of Type I interferon and dendritic cell (DC) maturation, which are desirable properties to exploit for vaccine design. We have previ...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Westcott, Marlena M., Smedberg, Jason, Jorgensen, Matthew J., Puckett, Shelby, Lyles, Douglas S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874657/
https://ncbi.nlm.nih.gov/pubmed/29562688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines6010016
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