A Polyamide Inhibits Replication of Vesicular Stomatitis Virus by Targeting RNA in the Nucleocapsid

Polyamides have been shown to bind double-stranded DNA by complementing the curvature of the minor groove and forming various hydrogen bonds with DNA. Several polyamide molecules have been found to have potent antiviral activities against papillomavirus, a double-stranded DNA virus. By analogy, we r...

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Bibliographic Details
Published in:J Virol
Main Authors: Gumpper, Ryan H., Li, Weike, Castañeda, Carlos H., Scuderi, M. José, Bashkin, James K., Luo, Ming
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5874401/
https://ncbi.nlm.nih.gov/pubmed/29437970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00146-18
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