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Impaired neuronal maturation of hippocampal neural progenitor cells in mice lacking CRAF

RAF kinases are major constituents of the mitogen activated signaling pathway, regulating cell proliferation, differentiation and cell survival of many cell types, including neurons. In mammals, the family of RAF proteins consists of three members, ARAF, BRAF, and CRAF. Ablation of CRAF kinase in in...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Pfeiffer, Verena, Götz, Rudolf, Camarero, Guadelupe, Heinsen, Helmut, Blum, Robert, Rapp, Ulf Rüdiger
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873938/
https://ncbi.nlm.nih.gov/pubmed/29590115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192067
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