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A Metagenome-Wide Association Study and Arrayed Mutant Library Confirm Acetobacter Lipopolysaccharide Genes Are Necessary for Association with Drosophila melanogaster

A metagenome wide association (MGWA) study of bacterial host association determinants in Drosophila predicted that LPS biosynthesis genes are significantly associated with host colonization. We were unable to create site-directed mutants for each of the predicted genes in Acetobacter, so we created...

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Vydáno v:G3 (Bethesda)
Hlavní autoři: White, K. Makay, Matthews, Melinda K., Hughes, Rachel C., Sommer, Andrew J., Griffitts, Joel S., Newell, Peter D., Chaston, John M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873903/
https://ncbi.nlm.nih.gov/pubmed/29487183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.300530
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