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Activity-Dependent Downscaling of Subthreshold Synaptic Inputs during Slow-Wave-Sleep-like Activity In Vivo

Activity-dependent synaptic plasticity is critical for cortical circuit refinement. The synaptic homeostasis hypothesis suggests that synaptic connections are strengthened during wake and downscaled during sleep; however, it is not obvious how the same plasticity rules could explain both outcomes. U...

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Publicat a:Neuron
Autors principals: González-Rueda, Ana, Pedrosa, Victor, Feord, Rachael C., Clopath, Claudia, Paulsen, Ole
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873548/
https://ncbi.nlm.nih.gov/pubmed/29503184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.047
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