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STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles

The centrosome linker proteins C-Nap1, rootletin, and CEP68 connect the two centrosomes of a cell during interphase into one microtubule-organizing center. This coupling is important for cell migration, cilia formation, and timing of mitotic spindle formation. Very little is known about the structur...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Vlijm, Rifka, Li, Xue, Panic, Marko, Rüthnick, Diana, Hata, Shoji, Herrmannsdörfer, Frank, Kuner, Thomas, Heilemann, Mike, Engelhardt, Johann, Hell, Stefan W., Schiebel, Elmar
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873239/
https://ncbi.nlm.nih.gov/pubmed/29463719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716840115
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