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Normal kinetics of intestinal glucose absorption in the absence of GLUT2: Evidence for a transport pathway requiring glucose phosphorylation and transfer into the endoplasmic reticulum

Glucose is absorbed through the intestine by a transepithelial transport system initiated at the apical membrane by the cotransporter SGLT-1; intracellular glucose is then assumed to diffuse across the basolateral membrane through GLUT2. Here, we evaluated the impact of GLUT2 gene inactivation on th...

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Detalhes bibliográficos
Main Authors: Stümpel, Frank, Burcelin, Rémy, Jungermann, Kurt, Thorens, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC58729/
https://ncbi.nlm.nih.gov/pubmed/11562503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211357698
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