Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone

BACKGROUND: Glia-mediated neuroinflammation is related to brain injury exacerbation after cerebral ischemia/reperfusion (I/R) injury. Astrocytic hemichannels or gap junctions, which were mainly formed by connexin-43, have been implicated in I/R damage. However, the exact roles of astrocytic hemichan...

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Publicat a:J Neuroinflammation
Autors principals: Yin, Xiang, Feng, Liangshu, Ma, Di, Yin, Ping, Wang, Xinyu, Hou, Shuai, Hao, Yulei, Zhang, Jingdian, Xin, Meiying, Feng, Jiachun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872583/
https://ncbi.nlm.nih.gov/pubmed/29587860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1127-3
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