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Investigation of model stacking for drug sensitivity prediction

BACKGROUND: A significant problem in precision medicine is the prediction of drug sensitivity for individual cancer cell lines. Predictive models such as Random Forests have shown promising performance while predicting from individual genomic features such as gene expressions. However, accessibility...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Matlock, Kevin, De Niz, Carlos, Rahman, Raziur, Ghosh, Souparno, Pal, Ranadip
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872495/
https://ncbi.nlm.nih.gov/pubmed/29589559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-018-2060-2
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