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Neurobiological Correlates of Pain Avoidance-Like Behavior in Morphine-Dependent and Non-Dependent Rats

Repeated use of opioids can lead to the development of analgesic tolerance and dependence. Additionally, chronic opioid exposure can cause a paradoxical emergence of heightened pain sensitivity to noxious stimuli, termed hyperalgesia, which may drive continued or escalated use of opioids to manage w...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: Pahng, Amanda R., Paulsen, Rod I., McGinn, M. Adrienne, Edwards, Kimberly N., Edwards, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872155/
https://ncbi.nlm.nih.gov/pubmed/29024786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.09.055
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