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Integrated Systems Approach Reveals Sphingolipid Metabolism Pathway Dysregulation in Association with Late-Onset Alzheimer’s Disease

Late-onset Alzheimer’s disease (LOAD) and age are significantly correlated such that one-third of Americans beyond 85 years of age are afflicted. We have designed and implemented a pilot study that combines systems biology approaches with traditional next-generation sequencing (NGS) analysis techniq...

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Библиографические подробности
Опубликовано в: :Biology (Basel)
Главные авторы: Malamon, John Stephen, Kriete, Andres
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872042/
https://ncbi.nlm.nih.gov/pubmed/29425116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology7010016
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