Načítá se...

The Impact of Protein Structure and Sequence Similarity on the Accuracy of Machine-Learning Scoring Functions for Binding Affinity Prediction

It has recently been claimed that the outstanding performance of machine-learning scoring functions (SFs) is exclusively due to the presence of training complexes with highly similar proteins to those in the test set. Here, we revisit this question using 24 similarity-based training sets, a widely u...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Biomolecules
Hlavní autoři: Li, Hongjian, Peng, Jiangjun, Leung, Yee, Leung, Kwong-Sak, Wong, Man-Hon, Lu, Gang, Ballester, Pedro J.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871981/
https://ncbi.nlm.nih.gov/pubmed/29538331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom8010012
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!