Electrophoretic cytopathology resolves ERBB2 forms with single-cell resolution

In addition to canonical oncoproteins, truncated isoforms and proteolysis products are implicated in both drug resistance and disease progression. In HER2-positive breast tumors, expression of truncated HER2 isoforms resulting from alternative translation and/or carboxy-terminal fragments (CTFs) res...

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Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Kang, Chi-Chih, Ward, Toby M., Bockhorn, Jessica, Schiffman, Courtney, Huang, Haiyan, Pegram, Mark D., Herr, Amy E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871910/
https://ncbi.nlm.nih.gov/pubmed/29872719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-018-0052-3
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