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Structural insights into the RNA methyltransferase domain of METTL16
N(6)-methyladenosine (m(6)A) is an abundant modification in messenger RNA and noncoding RNAs that affects RNA metabolism. Methyltransferase-like protein 16 (METTL16) is a recently confirmed m(6)A RNA methyltransferase that methylates U6 spliceosomal RNA and interacts with the 3′-terminal RNA triple...
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| Publié dans: | Sci Rep |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5871880/ https://ncbi.nlm.nih.gov/pubmed/29593291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23608-8 |
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