Cementoin–SLPI fusion protein binds to human monocytes and epithelial cells and shows higher biological activity than SLPI

Secretory Leukocyte Proteinase Inhibitor (SLPI) is an antiinflammatory peptide that blocks the activity of serine proteases, primarily the neutrophil elastase. In an attempt to direct the activity of SLPI on inflamed sites, a chimera consisting of the transglutaminase II substrate domain of trappin...

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Publicado en:Sci Rep
Main Authors: Maffía, Paulo C., Guerrieri, Diego, Villalonga, Ximena, Caro, Fiorella, Gómez, Sonia, Tateosian, Nancy, Bogado, Betiana P., Sánchez, Mercedes L., Ambrosi, Nella, Chuluyan, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871749/
https://ncbi.nlm.nih.gov/pubmed/29593284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23680-0
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