Impact of Aging, Cytomegalovirus Infection, and Long-Term Treatment for Human Immunodeficiency Virus on CD8(+) T-Cell Subsets

Both healthy aging and human immunodeficiency virus (HIV) infection lead to a progressive decline in naive CD8(+) T-cell numbers and expansion of the CD8(+) T-cell memory and effector compartments. HIV infection is therefore often considered a condition of premature aging. Total CD8(+) T-cell number...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Veel, Ellen, Westera, Liset, van Gent, Rogier, Bont, Louis, Otto, Sigrid, Ruijsink, Bram, Rabouw, Huib H., Mudrikova, Tania, Wensing, Annemarie, Hoepelman, Andy I. M., Borghans, José A. M., Tesselaar, Kiki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871714/
https://ncbi.nlm.nih.gov/pubmed/29619031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00572
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