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Association between a functional interleukin 6 receptor genetic variant and risk of depression and psychosis in a population-based birth cohort

OBJECTIVE: Interleukin 6 (IL-6) levels are commonly elevated in patients with depression and psychosis and in people who are at risk of developing these disorders. A common, functional variant in the IL6R gene (IL6R Asp358Ala; rs2228145 A > C) is known to dampen down inflammation by impairing IL6...

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Bibliographische Detailangaben
Veröffentlicht in:Brain Behav Immun
Hauptverfasser: Khandaker, Golam M., Zammit, Stanley, Burgess, Stephen, Lewis, Glyn, Jones, Peter B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871397/
https://ncbi.nlm.nih.gov/pubmed/29197507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2017.11.020
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