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Dissimilar flexibility of α and β subunits of human adult hemoglobin influences the protein dynamics and its alteration induced by allosteric effectors

The general question by what mechanism an “effector” molecule and the hemes of hemoglobin interact over widely separated intramolecular distances to change the oxygen affinity has been extensively investigated, and still has remained of central interest. In the present work we were interested in cla...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schay, Gusztáv, Kaposi, András D., Smeller, László, Szigeti, Krisztián, Fidy, Judit, Herenyi, Levente
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5871000/
https://ncbi.nlm.nih.gov/pubmed/29584765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194994
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