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Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells

BACKGROUND: Nucleocytoplasmic transport is a tightly regulated process carried out by specific transport machinery, the defects of which may lead to a number of diseases including cancer. Karyopherin alpha 7 (KPNA7), the newest member of the karyopherin alpha nuclear importer family, is expressed at...

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Publicado en:BMC Cancer
Autores principales: Vuorinen, Elisa M., Rajala, Nina K., Ihalainen, Teemu O., Kallioniemi, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870926/
https://ncbi.nlm.nih.gov/pubmed/29580221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4261-5
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