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Apparent heterogeneity of cardiac A(1) adenosine receptors as revealed by radioligand binding experiments on N-ethylmaleimide-treated membranes

While G protein-coupled receptors are often studied by analyzing antagonist radioligand: “cold” agonist inhibition curves using an independent site model, it is now clear that K(L) and K(H) values determined in these analyses are not reliable estimates of the affinities of the agonists for “free” an...

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Pubblicato in:Naunyn Schmiedebergs Arch Pharmacol
Autori principali: Leung, E., Jacobson, K.A., Green, R.D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870127/
https://ncbi.nlm.nih.gov/pubmed/1775196
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