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Identification of proteins that interact with mammalian peptide:N-glycanase and implicate this hydrolase in the proteasome-dependent pathway for protein degradation

Peptide:N-glycanase (PNGase) cleaves oligosaccharide chains from glycopeptides and glycoproteins. Recently the deduced amino acid sequence of a cytoplasmic PNGase has been identified in various eukaryotes ranging from yeast to mammals, suggesting that deglycosylation may play a central role in some...

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Autors principals: Park, Hangil, Suzuki, Tadashi, Lennarz, William J.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC58701/
https://ncbi.nlm.nih.gov/pubmed/11562482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.201393498
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