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Dysregulation of autophagy as a common mechanism in lysosomal storage diseases

The lysosome plays a pivotal role between catabolic and anabolic processes as the nexus for signalling pathways responsive to a variety of factors, such as growth, nutrient availability, energetic status and cellular stressors. Lysosomes are also the terminal degradative organelles for autophagy thr...

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Pubblicato in:Essays Biochem
Autori principali: Seranova, Elena, Connolly, Kyle J., Zatyka, Malgorzata, Rosenstock, Tatiana R., Barrett, Timothy, Tuxworth, Richard I., Sarkar, Sovan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869865/
https://ncbi.nlm.nih.gov/pubmed/29233882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170055
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