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Addressing the Opioid Crisis: The Importance of Choosing Translational Endpoints in Analgesic Drug Discovery

The opioid crisis has stimulated renewed interest in analgesic drug development. This effort will involve preclinical-to-clinical translational research and will benefit from a focus on endpoints that are both clinically relevant and shared across laboratory animals and humans. Measures of pain-rela...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Autor principal: Negus, S. Stevens
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869150/
https://ncbi.nlm.nih.gov/pubmed/29501211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2018.02.002
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