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Dysregulation of Rab5-Mediated Endocytic Pathways in Alzheimer’s Disease
Increasing evidence has pointed to that dysregulation of the endo-lysosomal system is an early cellular phenotype of pathogenesis for Alzheimer’s disease (AD). Rab5, a small GTPase, plays a critical role in mediating these processes. Abnormal overactivation of Rab5 has been observed in post-mortem b...
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| Publicat a: | Traffic |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869093/ https://ncbi.nlm.nih.gov/pubmed/29314494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tra.12547 |
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