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ES cell-derived presomitic mesoderm-like tissues for analysis of synchronized oscillations in the segmentation clock

Somites are periodically formed by segmentation of the anterior parts of the presomitic mesoderm (PSM). In the mouse embryo, this periodicity is controlled by the segmentation clock gene Hes7, which exhibits wave-like oscillatory expression in the PSM. Despite intensive studies, the exact mechanism...

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Dettagli Bibliografici
Pubblicato in:Development
Autori principali: Matsumiya, Marina, Tomita, Takehito, Yoshioka-Kobayashi, Kumiko, Isomura, Akihiro, Kageyama, Ryoichiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869006/
https://ncbi.nlm.nih.gov/pubmed/29437832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.156836
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