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ES cell-derived presomitic mesoderm-like tissues for analysis of synchronized oscillations in the segmentation clock

Somites are periodically formed by segmentation of the anterior parts of the presomitic mesoderm (PSM). In the mouse embryo, this periodicity is controlled by the segmentation clock gene Hes7, which exhibits wave-like oscillatory expression in the PSM. Despite intensive studies, the exact mechanism...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Matsumiya, Marina, Tomita, Takehito, Yoshioka-Kobayashi, Kumiko, Isomura, Akihiro, Kageyama, Ryoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869006/
https://ncbi.nlm.nih.gov/pubmed/29437832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.156836
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