Keratan Sulfate Phenotype in the β-1,3-N-Acetylglucosaminyltransferase-7–Null Mouse Cornea

PURPOSE: Synthesis of keratan sulfate (KS) relies on coordinated action of multiple enzymes, including the N-acetylglucosamine–transferring enzyme, β-1,3-N-acetylglucosaminyltransferase-7 (β3GnT7). A mouse model deficient in β3GnT7 was developed to explore structural changes in KS and the extracellu...

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Udgivet i:Invest Ophthalmol Vis Sci
Main Authors: Littlechild, Stacy L., Young, Robert D., Caterson, Bruce, Yoshida, Hideyuki, Yamazaki, Maya, Sakimura, Kenji, Quantock, Andrew J., Akama, Tomoya O.
Format: Artigo
Sprog:Inglês
Udgivet: The Association for Research in Vision and Ophthalmology 2018
Fag:
Cornea
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869001/
https://ncbi.nlm.nih.gov/pubmed/29625490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22716
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