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Inhalation delivery of proteins from ethanol suspensions

To circumvent inherent problems associated with pulmonary administration of aqueous-solution and dry-powder protein drugs, inhalation delivery of proteins from their suspensions in absolute ethanol was explored both in vitro and in vivo. Protein suspensions in ethanol of up to 9% (wt/vol) were readi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Choi, Won Seon, Murthy, G. G. Krishna, Edwards, David A., Langer, Robert, Klibanov, Alexander M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58690/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11562495/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.201413798
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