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Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration
Zebrafish regenerate cardiac tissue through proliferation of pre-existing cardiomyocytes and neovascularization. Secreted growth factors such as FGFs, IGF, PDGFs and Neuregulin play essential roles in stimulating cardiomyocyte proliferation. These factors activate the Ras/MAPK pathway, which is tigh...
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| Publicado no: | Development |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5868992/ https://ncbi.nlm.nih.gov/pubmed/29444893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.157206 |
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