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FGF2-dependent mesenchyme and laminin-111 are niche factors in salivary gland organoids

Epithelial progenitor cells are dependent upon a complex 3D niche to promote their proliferation and differentiation during development, which can be recapitulated in organoids. The specific requirements of the niche remain unclear for many cell types, including the proacinar cells that give rise to...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Hosseini, Zeinab F., Nelson, Deirdre A., Moskwa, Nicholas, Sfakis, Lauren M., Castracane, James, Larsen, Melinda
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868949/
https://ncbi.nlm.nih.gov/pubmed/29361536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.208728
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