Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex

Amino acid signaling mediated by the activation of mechanistic target of rapamycin complex 1 (mTORC1) is fundamental to cell growth and metabolism. However, how cells negatively regulate amino acid signaling remains largely unknown. Here, we show that interaction between 4F2 heavy chain (4F2hc), a s...

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Vydáno v:PLoS Biol
Hlavní autoři: Weng, Liang, Han, Yi-Peng, Enomoto, Atsushi, Kitaura, Yasuyuki, Nagamori, Shushi, Kanai, Yoshikatsu, Asai, Naoya, An, Jian, Takagishi, Maki, Asai, Masato, Mii, Shinji, Masuko, Takashi, Shimomura, Yoshiharu, Takahashi, Masahide
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868845/
https://ncbi.nlm.nih.gov/pubmed/29538402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2005090
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