Neisseria Heparin Binding Antigen is targeted by the human alternative pathway C3-convertase

Neisserial Heparin Binding Antigen (NHBA) is a surface-exposed lipoprotein specific for Neisseria and constitutes one of the three main protein antigens of the Bexsero vaccine. Meningococcal and human proteases, cleave NHBA protein upstream or downstream of a conserved Arg-rich region, respectively....

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Vydáno v:PLoS One
Hlavní autoři: Di Fede, Martina, Biagini, Massimiliano, Cartocci, Elena, Parillo, Carlo, Greco, Alessandra, Martinelli, Manuele, Marchi, Sara, Pezzicoli, Alfredo, Delany, Isabel, Rossi Paccani, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868813/
https://ncbi.nlm.nih.gov/pubmed/29579105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194662
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