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Engineered Janus probes modulate nucleic acid amplification to expand the dynamic range for direct detection of viral genomes in one microliter crude serum samples

The viral genome load in diverse clinical samples varies over several orders of magnitude (e.g. 1–10(4) copies per μL), thus a dynamic range-extended and sensitive analysis method is highly desired. However, existing well-developed nucleic acid amplification systems always suffer from either a limit...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Zhao, Yue, Chen, Feng, Qin, Jing, Wei, Jing, Wu, Wenhua, Zhao, Yongxi
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868314/
https://ncbi.nlm.nih.gov/pubmed/29629109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03994h
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