Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response

Although stop codon readthrough is used extensively by viruses to expand their gene expression, verified instances of mammalian readthrough have only recently been uncovered by systems biology and comparative genomics approaches. Previously, our analysis of conserved protein coding signatures that e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Loughran, Gary, Jungreis, Irwin, Tzani, Ioanna, Power, Michael, Dmitriev, Ruslan I., Ivanov, Ivaylo P., Kellis, Manolis, Atkins, John F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2018
Pynciau:
RNA
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868278/
https://ncbi.nlm.nih.gov/pubmed/29386352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.818526
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