High Frequency of Identical Clonal Immunoglobulin DNA in Pre-Treatment Tumor and Plasma from Untreated Patients with HIV-Associated Lymphoma: Prospective Multicenter Trial of the AIDS Malignancies Consortium (AMC 064)

Patients with HIV are at increased risk for developing B-cell lymphomas likely due in part to chronic antigen stimulation leading to clonal immunoglobulin (Ig) gene rearrangements. Clonal Ig DNA has been identified in the plasma in patients with lymphomas. However, next-generation sequencing (NGS)-b...

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Veröffentlicht in:Leuk Lymphoma
Hauptverfasser: Wagner-Johnston, Nina D., Lensing, Shelly, Noy, Ariela, Ratner, Lee, Henry, David, Lee, Jeannette Y., Silver, Sylvia, Faham, Malek, Ambinder, Richard F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867902/
https://ncbi.nlm.nih.gov/pubmed/28508728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1317095
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