Vildagliptin Can Alleviate Endoplasmic Reticulum Stress in the Liver Induced by a High Fat Diet

Purpose. We investigated whether a DDP-4 inhibitor, vildagliptin, alleviated ER stress induced by a high fat diet and improved hepatic lipid deposition. Methods. C57BL/6 mice received standard chow diet (CD), high fat diet (HFD), and HFD administered with vildagliptin (50 mg/Kg) (V-HFD). After admin...

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Publicado en:Biomed Res Int
Autores principales: Ma, Xiaoqing, Du, Wenhua, Shao, Shanshan, Yu, Chunxiao, Zhou, Lingyan, Jing, Fei
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867538/
https://ncbi.nlm.nih.gov/pubmed/29721506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5045182
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