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Detailed Characterization of T Cell Receptor Repertoires in Multiple Sclerosis Brain Lesions

The antigen-specific activation of pathogenic T cells is considered essential in the initiation and maintenance of multiple sclerosis (MS). The site of activation, the differential involvement of CD4+, and CD8+ T cells, their functional phenotype, and specificity, are important aspects to understand...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Planas, Raquel, Metz, Imke, Martin, Roland, Sospedra, Mireia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867461/
https://ncbi.nlm.nih.gov/pubmed/29616027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00509
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