Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study

OBJECTIVES: There is a need for effective and safe treatment during pregnancy in women with chronic inflammatory diseases. This study evaluated placental transfer of certolizumab pegol (CZP), an Fc-free anti-tumour necrosis factor drug, from CZP-treated pregnant women to their infants. METHODS: CRIB...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Mariette, Xavier, Förger, Frauke, Abraham, Bincy, Flynn, Ann D, Moltó, Anna, Flipo, René-Marc, van Tubergen, Astrid, Shaughnessy, Laura, Simpson, Jeff, Teil, Marie, Helmer, Eric, Wang, Maggie, Chakravarty, Eliza F
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Clinical and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867410/
https://ncbi.nlm.nih.gov/pubmed/29030361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2017-212196
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