Mast Cells Are Activated by Streptococcus pneumoniae In Vitro but Dispensable for the Host Defense Against Pneumococcal Central Nervous System Infection In Vivo

Mast cells reside on and near the cerebral vasculature, the predominant site of pneumococcal entry into the central nervous system (CNS). Although mast cells have been reported to be crucial in protecting from systemic bacterial infections, their role in bacterial infections of the CNS remained elus...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Fritscher, Johanna, Amberger, Daniel, Dyckhoff, Susanne, Bewersdorf, Jan Philipp, Masouris, Ilias, Voelk, Stefanie, Hammerschmidt, Sven, Schmetzer, Helga Maria, Klein, Matthias, Pfister, Hans-Walter, Koedel, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867309/
https://ncbi.nlm.nih.gov/pubmed/29616039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00550
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