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Norcantharidin, a clinical used chemotherapeutic agent, acts as a powerful inhibitor by interfering with fibrinogen–integrin α(II) (b)β(3) binding in human platelets
During platelet activation, fibrinogen binds to its specific platelet receptor, integrin α(II) (b)β(3), thus completing the final common pathway for platelet aggregation. Norcantharidin (NCTD) is a promising anticancer agent in China from medicinal insect blister beetle. In this study, we provided t...
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| Pubblicato in: | J Cell Mol Med |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5867116/ https://ncbi.nlm.nih.gov/pubmed/29369482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13488 |
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