IL‐21 promotes myocardial ischaemia/reperfusion injury through the modulation of neutrophil infiltration

BACKGROUND AND PURPOSE: The immune system plays an important role in driving the acute inflammatory response following myocardial ischaemia/reperfusion injury (MIRI). IL‐21 is a pleiotropic cytokine with multiple immunomodulatory effects, but its role in MIRI is not known. EXPERIMENTAL APPROACH: Myo...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Wang, Kejing, Wen, Shuang, Jiao, Jiao, Tang, Tingting, Zhao, Xin, Zhang, Min, Lv, Bingjie, Lu, Yuzhi, Zhou, Xingdi, Li, Jingyong, Nie, Shaofang, Liao, Yuhua, Wang, Qing, Tu, Xin, Mallat, Ziad, Xia, Ni, Cheng, Xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Themed Section: Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866974/
https://ncbi.nlm.nih.gov/pubmed/28294304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13781
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