Oxidized low‐density lipoprotein stimulates epithelial sodium channels in endothelial cells of mouse thoracic aorta

BACKGROUND AND PURPOSE: The epithelial sodium channel (ENaC) is expressed in endothelial cells and acts as a negative modulator of vasodilatation. Oxidized LDL (ox‐LDL) is a key pathological factor in endothelial dysfunction. In the present study we examined the role of ENaC in ox‐LDL‐induced endoth...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Liang, Chen, Wang, Qiu‐Shi, Yang, Xu, Niu, Na, Hu, Qing‐Qing, Zhang, Bao‐Long, Wu, Ming‐Ming, Yu, Chang‐Jiang, Chen, Xiao, Song, Bin‐Lin, Zhang, Zhi‐Ren, Ma, He‐Ping
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Themed Section: Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866960/
https://ncbi.nlm.nih.gov/pubmed/28480509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13853
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