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Crystal stuctures of MglB‐2 (TP0684), a topologically variant d‐glucose‐binding protein from Treponema pallidum, reveal a ligand‐induced conformational change

Previously, we determined the crystal structure of apo‐TpMglB‐2, a d‐glucose‐binding component of a putative ABC transporter from the syphilis spirochete Treponema pallidum. The protein had an unusual topology for this class of proteins, raising the question of whether the d‐glucose‐binding mode wou...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Brautigam, Chad A., Deka, Ranjit K., Liu, Wei Z., Norgard, Michael V.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866939/
https://ncbi.nlm.nih.gov/pubmed/29318719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3373
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