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Systematic characterization of pan‐cancer mutation clusters

Cancer genome sequencing has shown that driver genes can often be distinguished not only by the elevated mutation frequency but also by specific nucleotide positions that accumulate changes at a high rate. However, properties associated with a residue's potential to drive tumorigenesis when mut...

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Publicat a:Mol Syst Biol
Autors principals: Buljan, Marija, Blattmann, Peter, Aebersold, Ruedi, Boutros, Michael
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866917/
https://ncbi.nlm.nih.gov/pubmed/29572294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177974
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