Lesion Oxygenation Associates with Clinical Outcomes in Premalignant and Early Stage Head and Neck Tumors Treated on a Phase 1 Trial of Photodynamic Therapy

BACKGROUND: We report on a Phase 1 trial of photodynamic therapy (PDT) for superficial head and neck (H&N) lesions. Due to known oxygen dependencies of PDT, translational measurements of lesion hemoglobin oxygen saturation (S(t)O(2)) and blood volume (tHb) were studied for associations with pati...

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Detalhes bibliográficos
Publicado no:Photodiagnosis Photodyn Ther
Main Authors: Ahn, Peter H., Finlay, Jarod C., Gallagher-Colombo, Shannon M., Quon, Harry, O’Malley, Bert W., Weinstein, Gregory S., Chalian, Ara, Malloy, Kelly, Sollecito, Thomas, Greenberg, Martin, Simone, Charles B., McNulty, Sally, Lin, Alexander, Zhu, Timothy C., Livolsi, Virginia, Feldman, Michael, Mick, Rosemarie, Cengel, Keith A., Busch, Theresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866751/
https://ncbi.nlm.nih.gov/pubmed/29113960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pdpdt.2017.10.015
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