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Conserved mechanism of cell-wall synthase regulation revealed by the identification of a new PBP activator in Pseudomonas aeruginosa

Penicillin-binding proteins (PBPs) are synthases required to build the essential peptidoglycan (PG) cell wall surrounding most bacterial cells. The mechanisms regulating the activity of these enzymes to control PG synthesis remain surprisingly poorly defined given their status as key antibiotic targ...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Greene, Neil G., Fumeaux, Coralie, Bernhardt, Thomas G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866570/
https://ncbi.nlm.nih.gov/pubmed/29507210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717925115
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