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MAPK signaling couples SCF-mediated degradation of translational regulators to oocyte meiotic progression

RNA-binding proteins (RBPs) are important regulators of gene expression programs, especially during gametogenesis. How the abundance of particular RBPs is restricted to defined stages of meiosis remains largely elusive. Here, we report a molecular pathway that subjects two nonrelated but broadly evo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kisielnicka, Edyta, Minasaki, Ryuji, Eckmann, Christian R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866554/
https://ncbi.nlm.nih.gov/pubmed/29496961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715439115
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